Find JetBlue flights from South Carolina.

JetBlue's most popular flights from South Carolina.

$

  • Charleston (CHS)to

    Santo Domingo (SDQ)
    Depart 10/16/2026
    from
    $217
    one-way

    Charleston (CHS)to

    San Francisco (SFO)
    Depart 11/20/2026
    from
    $244
    one-way

    Charleston (CHS)to

    Orlando (MCO)
    Depart 11/16/2026
    from
    $172
    one-way

  • Charleston (CHS)to

    San Juan (SJU)
    Depart 11/15/2026
    from
    $223
    one-way

    Charleston (CHS)to

    Philadelphia (PHL)
    Depart 11/19/2026
    from
    $179
    one-way

    Charleston (CHS)to

    Los Angeles (LAX)
    Depart 11/27/2026
    from
    $663
    one-way

  • Charleston (CHS)to

    Detroit (DTW)
    Depart 09/22/2026
    from
    $1,077
    one-way

    Charleston (CHS)to

    Newark (EWR)
    Depart 11/27/2026
    from
    $397
    one-way

More everyday low fares from South Carolina.

$

Charleston (CHS)to

Boston (BOS)
Depart 10/24/2026

one-way

from
$110

Charleston (CHS)to

Fort Lauderdale (FLL)
Depart 10/10/2026

one-way

from
$144

Charleston (CHS)to

New York (JFK)
Depart 11/10/2026

one-way

from
$149

Charleston (CHS)to

Orlando (MCO)
Depart 11/16/2026

one-way

from
$172

Charleston (CHS)to

Philadelphia (PHL)
Depart 11/19/2026

one-way

from
$179

Charleston (CHS)to

Santo Domingo (SDQ)
Depart 10/16/2026

one-way

from
$217

Charleston (CHS)to

San Juan (SJU)
Depart 11/15/2026

one-way

from
$223

Charleston (CHS)to

San Francisco (SFO)
Depart 11/20/2026

one-way

from
$244

Charleston (CHS)to

Newark (EWR)
Depart 11/27/2026

one-way

from
$397

Charleston (CHS)to

Los Angeles (LAX)
Depart 11/27/2026

one-way

from
$663

Charleston (CHS)to

Detroit (DTW)
Depart 09/22/2026

one-way

from
$1,077

*Fares shown reflect recent availability (collected within 24 hours), subject to change at any time. Fares are one-way and reflect lowest available fare (which may be Main Base). Fares do not include baggage fees or optional services and additional restrictions apply.